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Conference articles · 2025

Performance Comparison of Quantum and Classical Machine Learning Models for Chronic Kidney Disease Prediction

2025 IEEE 49th Annual Computers, Software, and Applications Conference (COMPSAC) · Pages 788–793

Abstract

In this study, we develop and compare quantum and classical machine learning-based chronic kidney disease prediction models. We used the “Chronic_Kidney_Disease Data Set” of the UCI Machine Learning Repository. We performed data preprocessing and applied feature engineering techniques to select the best features. We developed two quantum machine learning-based models and two classical machine learning-based models. We used a hybrid classical-quantum environment for building quantum machine learning models. Finally, we compared the performances of all four models. We found that the Quantum Support Vector Machine performs best among the quantum models. The model’s accuracy was 95% with a k-fold cross-validation score of 94.5% and an ROC-AUC score of 0.987. Among the classical models, the Support Vector Machine showed the highest performance with an accuracy of 92.5%, a k-fold cross-validation score of 93.9%, and a ROC-AUC score of 0.974. Overall, the Quantum Support Vector Machine outperformed all other developed models in terms of accuracy and validation scores. If the quantum models can be executed in a quantum computer instead of a hybrid environment, the models will exhibit higher accuracy and faster execution time. As the models are precisely predicting chronic kidney disease with high accuracy, we believe this study will act as an inspiring framework in the less-investigated field of quantum machine learning-based chronic kidney disease prediction.

Publication details

Category
Conference articles
Authors & affiliations
  1. Parama SrideviUbicomp Lab, Computer Science Department, Marquette University, Milwaukee, WI, USA
  2. Paramita Basak UpamaUbicomp Lab, Computer Science Department, Marquette University, Milwaukee, WI, USA
  3. Masud RabbaniUbicomp Lab, Computer Science Department, Marquette University, Milwaukee, WI, USA
  4. Sheikh Iqbal AhamedUbicomp Lab, Computer Science Department, Marquette University, Milwaukee, WI, USA
Venue
2025 IEEE 49th Annual Computers, Software, and Applications Conference (COMPSAC)
Publisher
IEEE
Record
Pages 788–793
Published
2025
Cite this work

Parama Sridevi, Paramita Basak Upama, Masud Rabbani, Sheikh Iqbal Ahamed. “Performance Comparison of Quantum and Classical Machine Learning Models for Chronic Kidney Disease Prediction”. 2025 IEEE 49th Annual Computers, Software, and Applications Conference (COMPSAC), 788–793. (2025). https://doi.org/10.1109/COMPSAC65507.2025.00105.

Research topics

  • Quantum Machine Learning (QML)
  • Chronic Kidney Disease (CKD)
  • Feature Engineering
  • Quantum Support Vector Machine (QSVM)
  • Quantum Neural Network (QNN)
  • quantum machine learning
  • chronic kidney disease
  • quantum support-vector machine
  • feature engineering
  • UCI dataset
  • clinical prediction